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After nicotine is absorbed into the bloodstream and metabolized into cotinine, the kidneys filter it out of the blood and into the urine

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For example, you might choose to offer a mix of mild, medium, and full-bodied cigars, as well as flavored options for those who enjoy a sweeter smoke

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The team tried to limit expectation effects by recruiting only participants with no strong product preference, and the results in the nicotine replacement arm were at least as good as in routine practice